IGF-1 (Insulin-like Growth Factor 1) is a powerful anabolic growth factor – a hormone naturally produced in the liver in response to growth hormone (GH) stimulation.
Colostrum and certain milk peptides – naturally contain small amounts of IGF-1
None of these should be used casually – they alter endocrine systems and carry side effect profiles.
Key Takeaways
IGF-1 is a growth-regulating hormone activated by GH
It promotes muscle repair, skin health, bone density, and more
High IGF-1 = anabolic, but long-term overexpression may raise cancer risk
Compounds like MK-677 and GH peptides raise IGF-1 levels
IGF-1 is powerful – and shouldn’t be boosted recklessly
FAQ about IGF-1 (Insulin-Like Growth Factor 1)
Is IGF-1 a steroid? No. It’s a peptide hormone, not an anabolic steroid. It acts via the IGF-1 receptor – not the androgen receptor. Further reading: Are SARMs steroids?
What does IGF-1 do in the body? It helps build muscle, strengthen bone, repair tissues, and support metabolism – especially under the influence of growth hormone.
Can you increase IGF-1 naturally? Yes – via sleep, training, protein intake, and blood sugar control. GH-releasing stimuli also help.
Is IGF-1 safe to take? Endogenous (natural) IGF-1 is essential. However, long-term artificial elevation can pose risks, including potential cancer promotion.
Does IGF-1 affect skin and aging? Yes. It supports collagen synthesis, skin thickness, and wound healing – making it of interest in anti-aging protocols.
Androgen Receptor (AR) Definition:The androgen receptor (AR) is a type of nuclear receptor – a protein found inside cells that binds to androgens, the body’s natural male sex hormones such as testosterone and dihydrotestosterone (DHT). Once activated, it moves into the cell nucleus and switches on genes responsible for muscle growth, strength, and sexual development. …
A – Z Glossary Using This Glossary Feel free to bookmark this page and refer back whenever you encounter unfamiliar SARMs terminology. We update it regularly as new research and compounds emerge. Want this glossary embedded in your product or compound pages? Ask us about integrating it into your site layout or linking via tooltips. …
Definition: Anabolic Anabolic refers to any biological process that builds up complex molecules from simpler ones – the opposite of catabolic, which breaks things down.In the context of physiology and sports science, “anabolic” typically describes the growth and repair of muscle tissue, bone density, and other body structures through increased protein synthesis and cellular regeneration. …
Heard the term “PPARδ agonist” thrown around in fitness circles or SARMs forums?Usually in the same sentence as Cardarine (GW-501516)? You’re not alone. It sounds complex – but understanding this one term can help you grasp exactly how compounds like GW-501516 work to boost endurance and fat metabolism. Let’s break it down. What Is a …
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Glossary: What is IGF-1 (insulin-like growth factor 1)
IGF-1 (Insulin-like Growth Factor 1) is a powerful anabolic growth factor – a hormone naturally produced in the liver in response to growth hormone (GH) stimulation.
It plays a central role in:
Think of IGF-1 as the execution arm of growth hormone – GH gives the signal, IGF-1 gets the work done.
How IGF-1 Works (The Biological Pathway)
IGF-1 also enhances nutrient uptake, including amino acids and glucose, into muscle tissue.
Why Is IGF-1 Important?
IGF-1 is essential for normal human growth and recovery, especially during adolescence. In adults, it continues to regulate:
It also supports brain function, nerve regeneration, and immune modulation – making it relevant far beyond just fitness.
IGF-1 and Anabolism: Why Athletes Care
In performance circles, IGF-1 is sought after because of its:
It’s also central to how SARMs, GH peptides, and MK-677 (Ibutamoren) exert part of their effects.
Learn the differences: Are SARMs peptides?
IGF-1 vs Growth Hormone (GH): What’s the Difference?
Bottom line: GH gives the command – IGF-1 carries it out.
What Increases IGF-1 Naturally?
IGF-1 levels are often reduced in aging, calorie restriction, or chronic illness – which is why it’s explored in anti-aging and longevity research.
Learn more about increasing IGF with MK677
IGF-1 and Cancer Risk: The Double-Edged Sword
While IGF-1 promotes healthy tissue growth, excessive IGF-1 can also fuel unwanted cell proliferation – including cancer cells.
Epidemiological studies link very high IGF-1 levels with increased risk of:
This doesn’t make IGF-1 inherently dangerous – but it means context and control matter. Chronic elevation = risk.
IGF-1 in Supplements and Research
Some compounds used in research settings aim to increase IGF-1, including:
None of these should be used casually – they alter endocrine systems and carry side effect profiles.
Key Takeaways
FAQ about IGF-1 (Insulin-Like Growth Factor 1)
No. It’s a peptide hormone, not an anabolic steroid. It acts via the IGF-1 receptor – not the androgen receptor.
Further reading: Are SARMs steroids?
It helps build muscle, strengthen bone, repair tissues, and support metabolism – especially under the influence of growth hormone.
Yes – via sleep, training, protein intake, and blood sugar control. GH-releasing stimuli also help.
Endogenous (natural) IGF-1 is essential. However, long-term artificial elevation can pose risks, including potential cancer promotion.
Yes. It supports collagen synthesis, skin thickness, and wound healing – making it of interest in anti-aging protocols.
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